Buy Tamoxifen (Nolvadex)
Tamoxifen: Basic Information
Tamoxifen (Nolvadex), being an anti-estrogen, is used in sports to increase testosterone levels in men. Studies show a significant increase in testosterone levels (up to 42% in 10 days of taking 20 mg, and up to 83% when taken for more than a month and a half). This makes tamoxifen more effective than some other drugs, although self-medication is dangerous.
Tamoxifen 100tabs/20mg ZPHC
This is a rare, unique drug that belongs to the group of hormonal agents. Its use as prescribed, i.e. when it is personally prescribed by a doctor, is strictly individual and is prescribed only by a doctor. Self-medication with this drug is dangerous to health.
The drug acts very slowly. Its effect lasts for many hours. This is especially noticeable at the initial stage of administration.
For prevention and during PCT, to reduce unwanted side effects associated with increased estrogen levels, antiestrogens such as Letrozole and Tamoxifen are used. In bodybuilding, these drugs are used, but only under control, so as not to aggravate the situation.
The drug is used both during the course and during PCT. However, in some cases, PCT with Tamoxifen is not carried out, and athletes replace it with Clomid, which is more expensive, acts more safely and copes effectively.
Tamoxifen: Properties
Tamoxifen is a non-steroidal antiestrogen with weak estrogenic properties. It blocks estrogen receptors, competing with estradiol for binding in tissues (mammary gland, uterus, vagina, pituitary gland and tumors with a high content of estrogen receptors). Unlike estradiol, tamoxifen does not stimulate DNA synthesis, but, on the contrary, inhibits cell division, causing the death of tumor cells.
Pharmacokinetics:
Tamoxifen is well absorbed when taken orally. The maximum concentration in the blood is achieved after 3-7 hours. Equilibrium concentration - after 3-4 weeks of administration. Plasma protein binding is 99%. Metabolized in the liver. The half-life is biphasic: initial - 7-14 hours, terminal - 7 days. It is excreted mainly in the feces.
The drug is used in the prevention and treatment of gynecomastia, often in combination with other drugs such as clomiphene or antiaromatases. By the way, it is also effective in the treatment of peripheral precocious puberty in boys and girls, slowing bone growth and maturation and improving final height.
Differences between Clomiphene and Tamoxifen:
They are both antiestrogens, but with different mechanisms of action.
- Clomid - acts primarily on estrogen receptors in the pituitary gland, blocking negative feedback and stimulating the production of FSH and LH, which in turn increases testosterone production. Does not affect blood estrogen levels. More selective.
- Tamoxifen - blocks estrogen receptors throughout the body, including the pituitary gland, stimulating testosterone production, but less selectively than Clomid. Also does not affect the overall level of estrogen in the blood.
Differences and advantages of Tamoxifen:
- Despite less impact on the pituitary gland, it is as effective in restoring testosterone levels as Clomid.
- Blocks estrogens throughout the body, which prevents fluid retention.
- Cheaper than Clomid.
- Reduces cholesterol.
Disadvantages of tamoxifen:
- More toxic (nausea, loss of appetite, increased risk of thrombosis).
- Increases the number of progesterone receptors, which makes it incompatible with progestin drugs (Nandrolone, Trenbolone). In such cases, Clomid is preferable.
The choice between Clomid and tamoxifen depends on individual characteristics and concomitant drugs. It is important to remember that both drugs should only be used under strict medical supervision.
Effects:
| Pros | Cons |
| Treatment and prevention of breast cancer. Reduces the risk of developing cancer in women at high risk | Risk of adverse changes in cholesterol levels, which may increase the risk of cardiovascular disease |
| Increases bone mineral density in postmenopausal women | Preliminary data indicate a possible negative effect on the anabolic effect of steroids. |
| Prevents gynecomastia and female-type fat deposits in athletes by binding to estrogen receptors | Possible sleep disturbances and emotional fluctuations in some patients. |
| Positively affects cognitive function and protects brain cells | May cause changes in liver function in some individuals. |
| May be useful in neurodegenerative diseases such as Alzheimer's disease | Increases the likelihood of thromboembolic events, especially in predisposed individuals. |
Where to Buy Tamoxifen?
In 2001, worldwide sales of tamoxifen were about $1 billion. In 2002, the patent expired and generics began to be produced. By 2004, tamoxifen had become the best-selling hormonal drug for the treatment of breast cancer. By 2020, it was the 317th most commonly prescribed drug in the United States, with more than 900,000 prescriptions written.
On our website AnabolShop.org you will find drugs from famous brands all over the world, at the best prices and with fast delivery to all US states and Europe.
Example of a Course with Tamoxifen.
Introductory information: the concentration of the substance consumed and the duration of the course may vary depending on specific circumstances. It is recommended to have recent tests so that you can more accurately determine the required dose and regimen for taking tamoxifen.
Many people use it after a steroid cycle because of its availability. It helps the testicles restore testosterone production faster, which helps preserve muscle mass. However, it is worth considering that tamoxifen reduces estrogen levels, which can slow down the work of the testicles, making it not the best choice for PCT.
An alternative is clomiphene citrate, which is more effective in coping with the tasks of post-cycle therapy and is more recommended for these purposes. Although its cost is 2-3 times higher, the results are usually much better.
The drug dosages for post-cycle therapy (PCT) depend on the duration of the steroid cycle and individual hormone levels before the start of the course. Tamoxifen is used after most anabolic steroids, except for Nandrolone and Trenbolone.
Three schemes are presented:
- 6-week course: 20 days at 20 mg, 10 days at 10 mg + zinc (50 mg) + B6 (10 mg). A total of 50 tablets of 10 mg, duration of 30 days.
- 8-12-week course: 10 days at 40 mg, 25 days at 20 mg + zinc (50 mg) + B6 (10 mg), 10 days at 10 mg + zinc (50 mg) + B6 (10 mg). A total of 100 tablets of 10 mg, duration of 45 days.
- 16 weeks and more: 10 days at 60 mg, 30 days at 40 mg, 10 days at 20 mg, 10 days at 10 mg + zinc (50 mg) + B6 (10 mg). A total of 210 tablets of 10 mg, duration 60 days.
After completing tamoxifen, it is recommended to take zinc (25-30 mg), B6 (10 mg) and E (200 IU) for 30 days. After 2 months, hormone tests (FSH, progesterone, LH, prolactin, estradiol, SHBG, testosterone: free & total) should be taken. The choice of the scheme should be based on individual indicators.
Interesting! A study conducted at Ghent University in the late 1970s compared the effectiveness of tamoxifen (Nolvadex) and clomiphene in increasing testosterone levels in healthy men and men with oligospermia. The results showed that 10 days of tamoxifen 20 mg per day increased serum testosterone levels by 142%, which is comparable to the effect of 150 mg clomiphene per day (about three 50 mg tablets). Considering the roughly equivalent cost of 20 mg tamoxifen and 50 mg clomiphene, the study points to a more favorable price/effectiveness ratio in favor of tamoxifen.
Additional advices:
It is recommended to take hormone tests (LH, FSH, estradiol, testosterone) from the 15th day of PCT every 2 weeks to adjust tamoxifen intake and minimize side effects. It is worth having tamoxifen in reserve, and also using an aromatase inhibitor.
A course of tamoxifen can be combined with arginine (6-10 g per day), which helps burn fat and build muscle mass, and also get from food: nuts, pumpkin seeds, chicken eggs, milk and peas.
At the beginning of PCT, a week without physical activity is recommended, then a transition to average training. It is important to maintain a sleep schedule and add unsaturated fats, vegetables and seafood to the diet. It is also recommended to take vitamin E (400 IU per day) throughout the therapy.
Reviews & Price
Athletes appreciate the drug for its low price, which is its first plus, good efficiency in preventing gynecomastia and normalizing hormonal levels. On the other hand, side effects are mentioned, including nausea, loss of appetite, increased risk of thrombosis and others.
Its use should be under the supervision of a specialist in this field. The effectiveness and tolerability of the drug are individual.
Regarding the price, on average, for 50 tablets of 10 mg you will pay a total of about 10-15 dollars, although the price here depends on the manufacturer.
—————
Buy tamoxifen with delivery to the USA and Europe without a prescription - there is an opportunity on the official website!
Tamoxifen Reviews - the drug is great for PCT.
Tamoxifen Price - on average, the price depends on the manufacturer.
Good anabolism to all!