Buy Testosterone Undecanoate
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Testosterone Undecanoate10ml ZPHC 250mg/ml
In recent years, under the influence of advice from social networks and promises to get rid of problems associated with age-related changes, there has been a surge of interest in testosterone therapy and dietary supplements that increase its level. Men seeking to cope with decreased libido, uncertain erections, fatigue, loss of activity and zest for life, are increasingly turning to testosterone as a panacea. However, the availability of such miracle drugs only spurs demand and the need for competent consultation with a specialist.
But should we blindly trust this trend? In several Western countries, the opposite trend is already observed - men, aware of the potential risks, refuse hormone therapy even when there are medical indications.
Is testosterone as harmless as it seems at first glance?
Before deciding, it is important to understand the following:
- Testosterone is not a universal solution. It can be useful for certain medical conditions associated with a deficiency of this hormone, but it is not a magic pill for all problems.
- Dietary supplements are not a replacement for therapy. The effectiveness of dietary supplements that «increase» testosterone is often questionable, and uncontrolled use can be dangerous.
- Risks exist. Hormone therapy has its own side effects and contraindications that must be considered. But take everything under the supervision of a competent specialist or sports consultant.
The Problem of low Testosterone in Age
From about age 35, every man begins to experience a steady decline in testosterone levels, a key sex hormone responsible for maintaining healthy muscles, bones, libido, and overall activity. On average, testosterone production declines by about 2% each year, which over time can lead to significant consequences.
This gradual decline can result in hypogonadism, a condition characterized by critically low testosterone levels. Statistics show that hypogonadism occurs in every fifth man over 60, and the likelihood of its development increases proportionally to age.
But what exactly happens in the body when testosterone levels decline?
Firstly, with age, the activity of the Leydig cells located in the testicles and responsible for testosterone synthesis decreases. Secondly, the hypothalamic-pituitary system, which regulates the production of hormones, including testosterone, is disrupted. Thirdly, age-related changes in metabolism can affect testosterone metabolism, leading to its accelerated destruction.
And an excellent solution for such a problem is Testosterone Undecanoate. To get the maximum effect from the drug, it should be used correctly, and knowing the necessary dosages and cycles, and more on that below!
Features of Testosterone Undecanoate
Testosterone undecanoate is essentially a «precursor» to testosterone and is classified as an androgenic and anabolic-androgenic steroid (AAS). This means that it acts as an agonist at the androgen receptor (AR), stimulating its activity.
Once ingested, testosterone is metabolized in the liver into various 17-ketosteroids via two main pathways. It is important to note that the key active metabolites of testosterone are estradiol and dihydrotestosterone (DHT), each of which plays a different role in the body.
- Anabolic index - 100% in relation to testosterone.
- Androgenic index - also 100% in relation to testosterone.
- Aromatization - present, pronounced.
- Conversion to dihydrotestosterone (DHT) - present.
- Suppression of the hypothalamic-pituitary-gonadal axis - present, pronounced.
- Liver toxicity - absent.
- Method of administration - parenteral, in the form of intramuscular injections.
- Dosage - 250 mg/ml (in one ampoule) or 1000 mg/ml (4 ampoules of 250 mg).
An interesting study from 2013 examined the effects of testosterone undecanoate therapy on bone mineral density (BMD) and biochemical markers of bone turnover in older men with osteoporosis and low serum testosterone levels.
The results were encouraging even a low dose of testosterone undecanoate (20 mg per day) effectively increased BMD in the lumbar spine and femoral neck, and improved bone metabolism. Moreover, the effect was comparable to the results of treatment with a standard dose (40 mg per day). Importantly, no significant side effects on the prostate gland were detected.
The authors of the study concluded that low doses of testosterone undecanoate may be a safe and cost-effective option for the treatment of osteoporosis in elderly men with testosterone deficiency. However, they emphasize the need for further studies to confirm these findings and assess the long-term effects of therapy.
Example of Use of Testosterone Undecanoate
Let’s consider an example of using testosterone undecanoate as part of hormone replacement therapy (HRT). This process requires strict adherence to the protocol and an individual approach to each patient.
The HRT procedure using testosterone undecanoate includes the following stages:
- Initial assessment of testosterone levels: Before starting HRT, it is necessary to conduct a thorough assessment of the patient’s testosterone level in the blood. This is necessary to confirm its deficiency and determine the feasibility of hormone therapy.
- Individual selection of dosage: Determining the optimal dosage of testosterone undecanoate is a key point. The doctor must take into account the patient’s test results, general health, age and individual characteristics of the body.
- Administration of the drug and possible adjustments: Testosterone undecanoate is administered by injection. As a rule, injections are given every 10-14 weeks. It is important to understand that during therapy, dosage adjustments may be required depending on the individual response of the body and the dynamics of testosterone levels.
- Regular monitoring and control tests: During HRT, regular monitoring of testosterone levels in the blood is necessary. This allows you to track the effectiveness of the therapy, promptly identify possible deviations and adjust the dosage if necessary.
When considering testosterone undecanoate in the context of hormone replacement therapy (HRT), there are a number of advantages and disadvantages that need to be taken into account when choosing this drug.
Advantages of undecanoate:
One of the key advantages is the less frequent frequency of injections compared to other testosterone esters. This significantly increases the convenience of HRT for the patient, reducing the need for frequent visits to the doctor. Undecanoate ensures the maintenance of a stable level of testosterone in the blood over a long period of time. This avoids sharp fluctuations in hormonal levels, which can negatively affect well-being.
Disadvantages of undecanoate:
- High cost: The main disadvantage of undecanoate is its higher price compared to other forms of testosterone. This can be a significant factor when choosing a drug for HRT.
Recommended dosage of undecanoate:
The dosage of testosterone undecanoate for HRT is selected individually for each patient based on the results of tests and assessment of the clinical picture. As a rule, it is 800-1000 mg every 10-14 weeks.
Important: HRT using testosterone undecanoate should be carried out exclusively under the supervision of a qualified physician. Self-medication is unacceptable and can cause serious harm to health.
Explanation of the drug concentration:
The inscription «1 ampoule - 1000 mg / 4 ml» found on the undecanoate packaging means that one ampoule contains 1000 mg of the active substance (testosterone undecanoate), dissolved in 4 ml of solvent. Thus, the concentration of the solution is 250 mg / ml.
It is important to understand that the indicated weight includes the ester group. The actual content of pure testosterone in the drug is about 70%. However, for the convenience of dosage and calculations, the dosage is indicated in accordance with the information on the label.
Testosterone undecanoate is an effective drug for HRT, which has several advantages. However, the high cost and the need for qualified supervision require a balanced approach to its choice.
Effects (Pros & Cons):
Testosterone undecanoate, like other forms of testosterone, has a wide range of positive and side effects on the male body, especially in the context of hormone replacement therapy (HRT). Let’s consider the main ones:
| Pros | Cons |
| Testosterone is a key hormone for the growth and maintenance of muscle tissue. Testosterone undecanoate, by increasing the level of this hormone, stimulates protein synthesis and reduces its breakdown, which ultimately leads to an increase in muscle mass and strength. | Testosterone undecanoate undergoes aromatization, that is, it is converted into estrogen under the influence of the aromatase enzyme. Increased estrogen levels can cause the following side effects:
|
| Testosterone plays an important role in maintaining bone health. The drug increases the absorption of calcium and reduces its excretion from the body, which increases bone density and reduces the risk of osteoporosis. | Administering exogenous testosterone (such as undecanoate) suppresses the body’s own testosterone production. This occurs according to the principle of feedback: increased levels of the hormone signal the body that its own production can be reduced. This can lead to the following consequences:
|
| Promotes fat burning and muscle mass growth. The drug increases metabolism and increases energy expenditure, which helps reduce body fat. | Testosterone undecanoate can be converted to dihydrotestosterone (DHT), which in turn can cause the following side effects:
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| Affects mood regulation and overall well-being. Increasing testosterone levels with undecanoate can improve mood, reduce symptoms of depression, and increase feelings of well-being. | Testosterone undecanoate can negatively affect the lipid profile of the blood, increasing the level of «bad» cholesterol (LDL) and decreasing the level of «good» cholesterol (HDL). This can increase the risk of developing cardiovascular diseases such as:
|
| Testosterone plays a role in regulating sleep-wake cycles. Normalizing hormone levels can improve sleep quality. | In addition to the above, testosterone undecanoate may cause:
|
It is important to remember:
The positive effects of testosterone undecanoate are only manifested when used correctly under the supervision of a qualified physician. But in our store, you will find all high-quality drugs and steroids with an affordable price.
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