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Anastrozole: Basic Information

Anastrozole is a drug that blocks the action of aromatase, an enzyme that converts testosterone into estradiol (a female hormone). Simply put, it reduces the level of estradiol in the body. This is especially important when using steroids that tend to aromatize (convert to estradiol), since excess estradiol can negatively affect health.
Before talking about the use of this drug, it is worth understanding how estrogens affect men. Their role in the body is extensive and directly related to well-being and athletic performance. In general, hormonal balance is the key to health and success.
How does estradiol affect a man?
Let's talk about estrogens and their effect on men. As you know, estrogens are not only female hormones. They play a certain, albeit less significant, role in the male body. In moderate quantities, they are useful, but excess can lead to serious problems.
What is the benefit? Well, first of all, estrogens are involved in maintaining immunity. In addition, they are important for bone health, help regulate cholesterol levels and promote the production of growth hormone (GH) and insulin-like growth factor (IGF-1). They also affect the water-salt balance, improve glucose absorption and, yes, affect libido. In general, not such an insignificant role.
However, there is a downside to this. Excess estrogen can cause a number of unpleasant, and sometimes dangerous, side effects. These include:
- Fluid retention and edema. Imagine how this affects your form...
- Fatigue and decreased training efficiency. Your results will be worse.
- Acne is a problem familiar to many.
- Increased risk of prostate cancer - now that's serious.
- Increased blood clotting, which increases the risk of thrombosis.
- Cardiovascular diseases. Do we need to talk about the consequences?
- Hypertension (high blood pressure).
- Increased risk of stroke.
- Gynecomastia (enlarged breasts) - a nightmare for any man.
- Decreased libido (in some cases). Something went wrong.
- Female-pattern obesity.
- Increased sweating.
- Sleep disorders.
- Hair loss.
- Gastrointestinal problems.
You see, the picture is not the rosiest. Therefore, monitoring estrogen levels is a key point for men, especially for those who play sports and use steroids.
This is where aromatase inhibitors like Anastrozole come in. These are drugs that block the conversion of testosterone into estrogen. This drug originally developed to treat breast cancer, is widely used in sports, allowing you to reduce estrogen levels and, therefore, minimize the risks associated with their excess. However, remember, self-medication is dangerous! Always consult a doctor. A competent approach to dosage will ensure the effectiveness and safety of use.
Anastrozole: Application
The use of it is not a game, but a serious matter that requires caution and specialist consultation. Its main purpose is to control the level of estradiol, increased due to the use of aromatizing anabolic steroids. Beginners should generally avoid its use unless necessary.
The drug is used in two main cases:
- Prevention - in therapeutic doses before the start of a steroid course to prevent an increase in estradiol and the associated side effects. It's like insurance.
- Treatment - during a steroid course, if symptoms of excess estradiol appear (gynecomastia, fluid retention, etc.). This is already a fight against the consequences.
The dosage regimen depends on the specific steroid course and individual characteristics of the body. For example, when using fast-acting Testosterone Propionate, Anastrozole may be needed as early as the second week, and when using Testosterone Enanthate - from the third. It is always better to rely on blood tests for estradiol.
- Intake: preferably on an empty stomach, with plenty of water for better absorption.
- Regime: the «every other day» regimen is often recommended. That is, take one day, then don't the next.
- Dosage: 250 mcg every other day is usually enough, but to reduce estradiol by 50%, a dose of 0.5 to 1 mg may be required. These are very individual indications.
- Monitoring: regular blood tests for estradiol are mandatory to adjust the dosage according to indications. Checking 10-14 days after starting the course is a good idea.
It is important to understand that not all steroids aromatize equally. Testosterone esters are at risk. Methandienone and Oxandrolone aromatize weakly.
If long esters are used during the course (for example, Sustanon-250), it is recommended to conduct an estradiol test 3-4 weeks after the start of the course. At the first signs of gynecomastia, this supplement can help relieve symptoms, as can its analogue, Letrozole. But remember: this is only symptomatic treatment. The main thing is to control the estrogen level.
Where to Buy Anastrozole?
Do you know that you have a predisposition to this disease? Then keep these drugs on hand at all times. They are affordable. You can always buy them in the sports pharmacology store AnabolShop.org, at the best prices and with delivery to all US states and Europe!
Do not forget that before starting the cycle, be sure to consult a specialist doctor.
Positive & Side Effects
Pros | Cons |
Maintaining higher testosterone levels is beneficial for men with hyperestrogenism. | It may cause indigestion, nausea, and other stomach problems. |
The drug blocks the conversion of testosterone to estrogen, which is especially important in breast cancer, slowing tumor growth. | In rare cases, cardiovascular problems may occur. Mood changes. |
It can improve the effectiveness of treatment for breast cancer and other diseases that require lowering estrogen. | The drug may affect the level of cholesterol in the blood. |
Lowering estrogen levels and increasing testosterone can improve quality of life. | Some patients may experience headaches and dizziness. |
By blocking the action of estrogen, the drug can reduce the risk of osteoporosis. | Although the drug helps prevent osteoporosis, it may also increase the risk of developing it in some patients. |
As for side effects, most of them occur with excessive reduction of E2 (estradiol).

Anastrozole: During the Course
Anastrozole and its breakdown products are excreted from the body mainly in urine, with less than 10% excreted unchanged. The excretion process takes approximately 72 hours after taking a single dose. The half-life in the blood is 40-50 hours, which means that during this time the concentration of the drug in the blood is halved.
It is important to understand that the regimen for taking Anastrozole is a very individual matter. It depends on the dosage form of the drug, concomitant diseases, other medications taken and the purpose of use. Only a doctor can determine the optimal treatment regimen and dosage, strict adherence to which is necessary to achieve the desired effect and minimize side effects. Self-medication with this drug is extremely dangerous and can lead to unpredictable consequences.
Week | Testosterone Cypionate | Testosterone Propionate | Anastrozole | Clomid (on PCT) |
1 | 250 mg/week | - | – | – |
2 | 500 mg/weeky | - | - | – |
3 | 500 mg/week | - | 0,5 mg/every other day | – |
4 | 500 mg/week | - | 0,5 mg/every other day | – |
5 | 500 mg/week | - | 0,5 mg/every other day | – |
6 | 500 mg/week | - | 0,5 mg/every other day | – |
7 | 500 mg/week | - | 0,5 mg/every other day | - |
8 | - | 100 mg/every other day | 0,5 mg/every other day | - |
9 | 100 mg/every other day | – | 0,5 mg/every other day | - |
10 | – | – | – | 75 mg/day |
11 | – | – | – | 50 mg/day |
12 | – | – | – | 50 mg/day |
13 | – | – | – | 25 mg/day |
The table shows that you should not start taking Anastrozole at the same time as starting a course of steroids. This is due to the fact that steroids need time to start working. Using it from the first week of the course can lead to an excessive decrease in estradiol levels, which in itself has undesirable consequences.
The fact is that estradiol, although in moderate quantities, is necessary for the normal functioning of the body. Its excessive decrease can cause:
- Osteoporosis
- Increased fat mass
- Depressed mood
- Skin problems (dryness, acne)
- Urinary incontinence
- Increased risk of cardiovascular diseases
- Sleep disorders
- Decreased muscle mass and strength
- Fatigue and weakness
Therefore, it is important to maintain estradiol levels within normal limits. This requires regular monitoring of the level of this hormone using blood tests - before, during and after the steroid course. This will help the doctor adjust the dosage of Anastrozole and prevent both excess and deficiency of estradiol. Self-medication in this case is fraught with serious consequences.

Anastrozole Cost & Reviews
The price of Anastrozole varies depending on the manufacturer, the number of tablets in the package, and the place of purchase. As a guide, a package of 50 tablets of 1 mg can cost about $25, and a package of 30 tablets - about $20. However, these prices may vary depending on the manufacturer and other factors.
Our online Anabolshop.org store offers drugs of various brands, such as ZPHC, CanadaBioLabs and Spectrum.
Numerous reviews on thematic sports forums indicate the effectiveness of Anastrozole in reducing estradiol levels when the correct regimen and dosage are followed. However, it is necessary to remember that the effectiveness and safety of the drug depend on the individual characteristics of the body and strict adherence to the doctor's recommendations. Positive reviews do not replace a specialist consultation. The negative consequences of improper use can be serious.
In our online store you will find a huge selection of not only aromatase inhibitors, but also many anti-estrogen drugs.
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Buy Anastrozole with delivery in the USA and in Europe without a prescription - there is an opportunity on the official website!
Anastrozole Reviews - the drug perfectly reduces the concentration of estradiol, but do not overdo it.
Anastrozole Price - on average, the price depends on the manufacturer.
Good anabolism to all!